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Potential effects of PFAS exposure on trained immunity: From mechanisms to health risks

28 Jul 2025

Abstract excerpt

Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are a class of persistent organic pollutants that are widely used in industry and consumption due to their unique chemical properties, but their extreme persistence and bioaccumulation potential pose significant risks to human health. There is growing evidence that PFAS exposure may disrupt trained immunity-a novel form of innate immune memory driven by...

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PMID: 40729912
DOI: 10.1016/j.ecoenv.2025.118757

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