Article

Phloiokeratosis – a new ichthyosiform hyperkeratotic cornification disorder in dogs with <i>SUV39H1</i> variants

2026-02-10

Abstract excerpt

The continuous renewal of healthy epidermis depends on the finely regulated proliferation of basal keratinocytes and subsequent differentiation as the newly formed cells move upwards through the different layers of the epidermis. Perturbations in keratinocyte differentiation may lead to cornification disorders. We investigated seven dogs of different breeds belonging to four independent families that showed striki...

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Literature Corpus work: e5ed2841-9a55-5ee7-92fe-57134a269204
DOI: 10.64898/2026.02.09.704839

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