Article
A splice site variant in the SUV39H2 gene in Greyhounds with nasal parakeratosis.
Animal genetics - 1 Apr 2018
Bauer A, Nimmo J, Newman R, Brunner M, Welle M M, Jagannathan V, Leeb T
Abstract excerpt
Hereditary nasal parakeratosis (HNPK), described in the Labrador Retriever breed, is a monogenic autosomal recessive disorder that causes crusts and fissures on the nasal planum of otherwise healthy dogs. Our group previously showed that this genodermatosis may be caused by a missense variant located in the SUV39H2 gene encoding a histone 3 lysine 9 methyltransferase, a chromatin modifying enzyme with a potential...
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