Article
Recent advances in understanding ichthyosis pathogenesis
2016-06-24
Abstract excerpt
The ichthyoses, also known as disorders of keratinization (DOK), encompass a heterogeneous group of skin diseases linked by the common finding of abnormal barrier function, which initiates a default compensatory pathway of hyperproliferation, resulting in the characteristic clinical manifestation of localized and/or generalized scaling. Additional cutaneous findings frequently seen in ichthyoses include generalize...
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Identifiers and source
- Literature Corpus work
- 5d0c3988-66fc-58b1-ab2c-94e0905e934e
- DOI
- 10.12688/f1000research.8584.1