Article

Stronger Microstructural Damage Revealed in Multiple Sclerosis Lesions with Central Vein Sign by Quantitative Gradient Echo MRI

2021-07-22

Abstract excerpt

<h4>Background</h4> Multiple sclerosis (MS) lesions typically form around a central vein that can be visualized with FLAIR* MRI, creating the central vein sign (CVS) which may reflect lesion pathophysiology. Herein we used Gradient Echo Plural Contrast Imaging (GEPCI) MRI to simultaneously visualize CVS and measure tissue damage in MS lesions. We examined CVS in relation to tissue integrity in white matter (WM) le...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e5cfa10c-551d-5601-9684-d2fa1dd60cf2
DOI: 10.1101/2021.07.17.21260663

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Stronger Microstructural Damage Revealed in Multiple Sclerosis Lesions with Central Vein Sign by Quantitative Gradient Echo MRIDOI 10.1101/2021.07.17.21260663Read

Comparative evaluation of EPI and SWI for the assessment of PRL and CVS in Multiple SclerosisSemantic proximity Read

Standard Model Imaging for Discriminating Multiple Sclerosis Lesion Types: A Lesion-Focused Analysis Compared with Diffusion Tensor ImagingSemantic proximity Read

Multiparametric Characterization and Spatial Distribution of Different MS Lesion Phenotypes.Semantic proximity Read

Diffusion-based structural connectivity patterns of multiple sclerosis phenotypesSemantic proximity Read

DeepFLAIR*: Improving Multiple Sclerosis Diagnostic Imaging Workflow Using Deep LearningSemantic proximity Read

Perivascular Space Semi-Automatic Segmentation (PVSSAS): A Tool for Segmenting, Viewing and Editing Perivascular SpacesSemantic proximity Read

Intrinsic damage to the major white matter tracts in patients with different clinical phenotypes of multiple sclerosis: a voxelwise diffusion-tensor MR study.Semantic proximity Read

Deep grey matter volume loss drives disability worsening in multiple sclerosisSemantic proximity Read

MPRAGE-derived quantitative T <sub>1</sub> mapping to assess diffuse white matter alterations in multiple sclerosisSemantic proximity Read

Investigating Mood and Cognition in People with Multiple Sclerosis: A Prospective Study ProtocolSemantic proximity Read

Fluid and White Matter Suppression Contrasts MRI Improves Deep Learning Detection of Multiple Sclerosis Cortical LesionsSemantic proximity Read

Diffusion-based structural connectivity patterns of multiple sclerosis phenotypes.Semantic proximity Read