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Increasing CYLD expression improved the prognosis by downregulating the mTOR/SREBP1/lipid metabolism pathway in HPV-negative OSCC patients

2025-05-30

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>CYLD is associated with tumorigenesis, but its role in HPV-negative OSCC is unclear. <bold>Methods and Results: </bold>R-bioinformatics analysis from the GEO database and qPCR analysis of OSCC cell lines demonstrated that CYLD mRNA expression was significantly reduced in OSCC compared to normal tissue and normal human gingival epithelial cell lines. In 66 primar...

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Literature Corpus work
e5964878-bf4d-5b76-9692-adec4ba79c2f
DOI
10.21203/rs.3.rs-6695111/v1
Open publication

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Increasing CYLD expression improved the prognosis by downregulating the mTOR/SREBP1/lipid metabolism pathway in HPV-negative OSCC patientsDOI 10.21203/rs.3.rs-6695111/v1
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