Article

Integrated analysis of bulk and single cell datasets with experimental validation of cancer stemness function in thyroid cancer prognosis and immunotherapy

2024-10-25

Abstract excerpt

<title>Abstract</title> <p>Cancer stem cells (CSCs) are vital in tumor development, immune therapy resistance, and thyroid carcinoma (THCA) advancement. Nonetheless, the exact mechanisms are still unclear. In this study, 28 mRNAs linked to cancer stemness were identified through an analysis of 13 publicly available THCA transcriptomic datasets alongside a CRISPR dataset for thyroid cancer cell lines. Importantly,...

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Literature Corpus work: e4fdfb7a-487c-5116-b00f-8b98cf3a4fdb
DOI: 10.21203/rs.3.rs-5314905/v1

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