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Identification of a Cancer Stemness Driven Prognostic Model and Therapeutic Drug Targets by Machine Learning in Hepatocellular Carcinoma

2021-12-22

Abstract excerpt

<h4>Background: </h4> Hepatocellular carcinoma (HCC) is one of the most common malignancies. Cancer stem cells (CSCs), characterized by self-renewal and drug-resistance, play an important role in the development and progression of diverse cancers, but the underlying association of HCC and CSCs is not fully researched. <h4>Methods: </h4>: Transcriptome and clinical data of 903 patients in four independent HCC cohor...

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Literature Corpus work
9405da41-d3d0-595a-85f2-ad9142568f1d
DOI
10.21203/rs.3.rs-1161100/v1
Open publication

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