Article

Curli Carrier Burden: a quantitative trait-level microbiome index for amyloidogenic bacterial signals in Parkinson’s disease gut metagenomes

2026-05-28

Abstract excerpt

<h4>Background</h4> Parkinson’s disease (PD) gut metagenomic studies have repeatedly reported disease-associated shifts in microbial taxa, genes, and pathways. However, the field still lacks transparent trait-level indices that summarize biologically coherent microbial exposures. Curli fibres are extracellular bacterial amyloids produced by several Enterobacteriaceae and related taxa, and they provide a plausible...

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Literature Corpus work: e4f2dab1-2388-5121-b273-f31eda27cd2e
DOI: 10.64898/2026.05.25.727557

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