Article
Epsilon Toxin Induces Cytotoxicity by Mediating Autophagy and Apoptosis Processes via the PI3K/AKT/mTOR Signaling Pathway in A549 Cells
2024-04-24
Abstract excerpt
<title>Abstract</title> <p>Background Epsilon toxin, synthesized by <italic>Clostridium perfringens</italic>, is a toxin from the class of pore-forming proteins that are associated with the development of enterotoxaemia in ruminants. As an agent of bioterrorism, exposure of toxin aerosol form causes endothelial cell damage and cytotoxicity in human lung cells. However, little information is available regarding t...
Topics
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- Bacterial biofilms and quorum sensing
- Clostridium difficile and Clostridium perfringens research
- Fungal Biology and Applications
- Pharmacological Effects of Natural Compounds
- Probiotics and Fermented Foods
- Streptococcal Infections and Treatments
- Tannin, Tannase and Anticancer Activities
- Toxin Mechanisms and Immunotoxins
Identifiers and source
- Literature Corpus work
- e4edc05f-f92e-5236-aed9-e5f403d2bc7a
- DOI
- 10.21203/rs.3.rs-4283904/v1
