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Epsilon Toxin Induces Cytotoxicity by Mediating Autophagy and Apoptosis Processes via the PI3K/AKT/mTOR Signaling Pathway in A549 Cells

2024-04-24

Abstract excerpt

<title>Abstract</title> <p>Background Epsilon toxin, synthesized by <italic>Clostridium perfringens</italic>, is a toxin from the class of pore-forming proteins that are associated with the development of enterotoxaemia in ruminants. As an agent of bioterrorism, exposure of toxin aerosol form causes endothelial cell damage and cytotoxicity in human lung cells. However, little information is available regarding t...

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Literature Corpus work
e4edc05f-f92e-5236-aed9-e5f403d2bc7a
DOI
10.21203/rs.3.rs-4283904/v1
Open publication

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Epsilon Toxin Induces Cytotoxicity by Mediating Autophagy and Apoptosis Processes via the PI3K/AKT/mTOR Signaling Pathway in A549 CellsDOI 10.21203/rs.3.rs-4283904/v1
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