Article

MutationAssessor in cBioPortal

2025-08-12

Abstract excerpt

MutationAssessor (MA) helps researchers evaluate the likely functional impact of somatic and germline mutations in cancer. It provides an evolution-based functional impact score (FIS) to classify mutations based on their likely effect on protein function. FIS scores are based on analysis of patterns of conservation in protein families (conserved residues) and subfamilies (specificity residues). In this new version...

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Literature Corpus work: e482ad01-383f-5b10-98ee-50e67a56130f
DOI: 10.1101/2025.08.10.669566

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