Article

Integration of Mechanistic Immunological Knowledge into a Machine Learning Pipeline Increases Predictive Power

2020-02-27

Abstract excerpt

The dense network of interconnected cellular signaling responses quantifiable in peripheral immune cells provide a wealth of actionable immunological insights. While high-throughput single-cell profiling techniques, including polychromatic flow and mass cytometry, have matured to a point that enables detailed immune profiling of patients in numerous clinical settings, limited cohort size together with the high dim...

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Literature Corpus work: cc26e93d-09f9-5c2b-b009-c0760e5410c2
DOI: 10.1101/2020.02.26.967232

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