Article

Therapeutic evaluation of palbociclib and its compatibility with other chemotherapies for primary and recurrent nasopharyngeal carcinoma

2020-10-30

Abstract excerpt

<h4>Background: </h4> Recent genomic analyses revealed that druggable molecule targets were detectable in approximately 6% of patients with nasopharyngeal carcinoma (NPC). However, a dependency on dysregulated CDK4/6–cyclinD1 pathway signaling is an essential event in the pathogenesis of NPC. In this study, we aimed to evaluate the therapeutic efficacy of a specific CDK4/6 inhibitor, palbociclib, and its compatibi...

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Literature Corpus work: e4149f77-2978-5a3b-a581-f9c2f818b2f3
DOI: 10.21203/rs.3.rs-36929/v2

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