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Identification of transcriptional network disruptions in drug-resistant prostate cancer with TraRe

2022-05-11

Abstract excerpt

Metastatic castration-resistant prostate cancer (mCRPC) presents very low survival rates due to lack of response or acquired resistance to the available therapies. To date no molecular mechanisms of resistance have been identified, pointing out their complex dynamics. To identify key genes and processes associated with phenotypically-driven regulatory differences, we developed TraRe, a computational method that pr...

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Literature Corpus work
e3e6c6bc-94e7-5a95-b9d7-d8d9901f5579
DOI
10.1101/2022.05.10.491360
Open publication

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Identification of transcriptional network disruptions in drug-resistant prostate cancer with TraReDOI 10.1101/2022.05.10.491360
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