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Integrated multi-omics profiling of immune microenvironment and drug resistance signatures for precision prognosis in prostate cancer

25 Jun 2025

Abstract excerpt

Introduction: Prostate cancer (PCa) continues to be a significant cause of mortality among men, with treatment resistance often influenced by the complexity of the tumor microenvironment (TME). This study aims to develop an immune-centric prognostic model that correlates TME dynamics, genomic instability, and the heterogeneity of drug resistance in PCa. Methods: Multi-omics data from The Cancer Genome Atlas...

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PMID: 40843359
DOI: 10.20517/cdr.2025.47

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