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Transgenic human dipeptidyl peptidase-4 Syrian hamsters support MERS coronavirus infection and contact transmission

2026-05-26

Abstract excerpt

Middle East respiratory syndrome coronavirus (MERS-CoV) is a global health concern due to a high fatality rate associated with human infections and no approved vaccines or therapeutics. While Syrian hamsters are a value animal model for coronavirus research, including SARS-CoV-2, MERS-CoV does not infect wild-type hamsters. Here, we generated transgenic Syrian hamsters expressing human dipeptidyl peptidase-4 (hDPP...

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Literature Corpus work
e3e6933c-206c-5cdc-bdf1-f4edbba59977
DOI
10.64898/2026.05.26.725122
Open publication

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Transgenic human dipeptidyl peptidase-4 Syrian hamsters support MERS coronavirus infection and contact transmissionDOI 10.64898/2026.05.26.725122
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