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First evaluation of a human DPP4 transgenic hamster model for MERS-CoV pathogenesis and transmission

2026-05-26

Abstract excerpt

MERS-CoV poses a constant pandemic risk, as its viral lineages continue evolving, and zoonotic spillover events could lead to random viral polymorphisms that might lead to human adapted variants. Currently, no small animal model reliably recapitulates both disease progression and transmission dynamics, which are critical aspects for counter-viral measures like vaccine development. Although the Syrian hamster is an...

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Literature Corpus work
517f768a-d171-596d-93d0-7ac8d4f2cef8
DOI
10.64898/2026.05.26.727115
Open publication

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First evaluation of a human DPP4 transgenic hamster model for MERS-CoV pathogenesis and transmissionDOI 10.64898/2026.05.26.727115
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