Back to search

Article

Single-nuclei transcriptome of brain-dead donor heart with long QT syndrome revealed neuronal modulation of cardiac immunity

2024-04-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Brain dead (BD) donor hearts with long QT syndrome (LQTS) showed accelerated cardiac allograft vasculopathy (CAV). We determine the differences between non-arrhythmic and LQTS myocardium through single-nuclei RNA sequencing (snRNAseq) analysis. <bold>Methods: </bold>16 non-arrhythmic and 4 LQTS BD donors myocardial snRNAseq were retrieved. Propensity score match...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e3e11ad4-29fa-5f3c-9c8c-72db3aac422b
DOI
10.21203/rs.3.rs-4286386/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Single-nuclei transcriptome of brain-dead donor heart with long QT syndrome revealed neuronal modulation of cardiac immunityDOI 10.21203/rs.3.rs-4286386/v1
Single-Cell RNA Sequencing Reveals the Altered Landscape of Immune Cells in Immune Checkpoint Inhibitor Related MyocarditisSemantic proximity
Myocardial B cells have specific gene expression and predicted interactions in Dilated Cardiomyopathy and Arrhythmogenic Right Ventricular CardiomyopathySemantic proximity
Single nucleus RNA-sequencing reveals altered intercellular communication and dendritic cell activation in nonobstructive hypertrophic cardiomyopathySemantic proximity
Persistent transcriptional changes in cardiac adaptive immune cells following myocardial infarction: New evidence from the re-analysis of publicly available single cell and nuclei RNA-sequencing data setsSemantic proximity
Single-cell RNA Sequencing of Peripheral Blood Mononuclear Cells in Patients with Single Ventricle/Hypoplastic Left Heart SyndromeSemantic proximity
Progress of Single-Cell RNA Sequencing Technology in Myocardial Infarction ResearchSemantic proximity
Identification of predictors for neurological outcome after cardiac arrest in peripheral blood mononuclear cells through integrated bioinformatics analysis and machine learningSemantic proximity
Utilizing Single-cell RNA Sequencing for Analyzing the Characteristics of PBMC in Patients with Kawasaki DiseaseSemantic proximity
Single-nuclear RNA sequencing of endomyocardial biopsies identifies persistence of donor-recipient chimerism with distinct signatures in severe cardiac allograft vasculopathySemantic proximity
Risk prediction model construction for heart failure after myocardial infarction by immune B cells in bloodSemantic proximity
Molecular Pathophysiology of Cardiac Injury and Cardiac Microthrombi in Fatal COVID-19: Insights from Clinico-histopathologic and Single Nuclei RNA Sequencing AnalysesSemantic proximity
Characterization of Natural Killer Cell Subpopulations in the Blood of Single Ventricle/Hypoplastic Left Heart Syndrome Patients Using Single-Cell RNA SequencingSemantic proximity
Select a neighboring publication to make it the new centre.