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Immune Antibodies Recognizing the Stem Region of SARS-CoV-2 Spike Protein: Molecular Modelling and <i>In Vitro</i> Study of Synthetic Peptides Presentation to the Antibodies

2025-03-21

Abstract excerpt

Antibodies to peptide 1147 (amino acids 1147-61) of the SARS-CoV-2 protein S are highly diagnostic. Peptide 1147, although located in a region that is partly spatially hidden in the intact protein, is not subject to mutations, suggesting therapeutic potential. The aim of this study was to elucidate the architecture of this region and the way in which it is presented to antibodies. As a model system, this peptide c...

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Literature Corpus work
e39d51e4-0198-596c-b306-566b8bd2330f
DOI
10.1101/2025.03.20.644166
Open publication

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Immune Antibodies Recognizing the Stem Region of SARS-CoV-2 Spike Protein: Molecular Modelling and <i>In Vitro</i> Study of Synthetic Peptides Presentation to the AntibodiesDOI 10.1101/2025.03.20.644166
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