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50 Years of structural immunology

1 Jan 2021

Abstract excerpt

Fifty years ago, the first landmark structures of antibodies heralded the dawn of structural immunology. Momentum then started to build toward understanding how antibodies could recognize the vast universe of potential antigens and how antibody-combining sites could be tailored to engage antigens with high specificity and affinity through recombination of germline genes (V, D, J) and somatic mutation. Equivalent...

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PMID: 33957119
DOI: 10.1016/j.jbc.2021.100745

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