Article

Tyrosine kinase inhibitors in cancer treatment (Part II)

1998-12-01

Abstract excerpt

In the last few years, enormous progress in the field of signal transduction inhibition has been made. Many companies have entered the field. Along with the epidermal growth factor receptor (EGFR) tyrosine kinase, many other tyrosine kinases have been identified as interesting targets for drug discovery projects. X-ray data of more than 40 crystal structures of protein kinases, in most cases complexed with an inhi...

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Literature Corpus work: e334e2c7-9530-5ec6-9bfd-40a4a0a0212d
DOI: 10.1517/13543776.8.12.1599

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