Article
Breast cancer clustering integrating complete gene expression profiles and genetic ancestry.
PloS one - 1 Jan 2026
Stepanian Johanna, Mejia-Garcia Alejandro, Orozco Carlos, Duitama Jorge
Abstract excerpt
Breast cancer (BC) remains the leading cause of cancer-related mortality among women globally. Precise subtyping of BC is critical for optimizing treatment strategies. This study explored the capacity of bulk RNA-seq data to improve breast cancer characterization by analysis of complete expression profiles. We analyzed RNA-seq data for 274 tumor samples and six healthy tissue samples from diverse geographical...
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