Back to search

Article

Quantifying stem cell derived islet graft volume and composition with [ <sup>18</sup> F]F-DBCO-exendin and [ <sup>18</sup> F]FDOPA positron emission tomography

2023-12-18

Abstract excerpt

Stem cell derived islets (SC-islets) are being developed as a novel source of beta cells that would enable large scale cell replacement therapy for insulin dependent diabetes. Therapeutic use of SC-islets carries an inherent risk of unwanted growth; and multiple strategies are being explored for optimizing long-term SC-islet graft effectiveness. However, a method for noninvasive in vivo monitoring for SC-islet gr...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
e28eadbe-3fbc-5036-9090-15b2c50ecda8
DOI
10.1101/2023.12.18.572141
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 8 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Quantifying stem cell derived islet graft volume and composition with [ <sup>18</sup> F]F-DBCO-exendin and [ <sup>18</sup> F]FDOPA positron emission tomographyDOI 10.1101/2023.12.18.572141
Deep tissue optical 3D imaging reveals preferential preservation of extra-islet β-cells in late-onset Type 1 DiabetesSemantic proximity
Long-term monitoring of transplanted islets using positron emission tomography.Semantic proximity
Functional Beta Cell Mass from Device-Encapsulated hESC-Derived Pancreatic Endoderm Achieving Metabolic ControlSemantic proximity
Optimizing Post-Transplantation Detection of Subcutaneously Transplanted Islets Using Dithizone StainingSemantic proximity
Peptide-Mediated Targeting of the Islets of LangerhansSemantic proximity
In Situ Analysis Reveals That CFTR Is Expressed in Only a Small Minority of β-Cells in Normal Adult Human PancreasSemantic proximity
Longitudinal three-dimensional visualisation of autoimmune diabetes by functional optical coherence imaging.Semantic proximity
Endocrine-enriched stem cell-derived islets improve long-term safety <i>in vivo</i>Semantic proximity
Select a neighboring publication to make it the new centre.