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Article

Early-life immune activation is a vulnerability factor for adult epileptogenesis in neurofibromatosis type 1

2023-11-03

Abstract excerpt

<h4>Introduction</h4> Patients with Neurofibromatosis type 1 (NF1), the most common neurocutaneous disorder, can develop several neurological manifestations that include cognitive impairments and epilepsy over their lifetime. It is unclear why certain patients with NF1 develop these conditions while others do not. Early-life immune activation promotes later-life seizure susceptibility, neurocognitive impairments,...

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Literature Corpus work
e25a7093-ad7b-5cc7-bf47-7e6c9be81a64
DOI
10.1101/2023.10.31.564967
Open publication

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Early-life immune activation is a vulnerability factor for adult epileptogenesis in neurofibromatosis type 1DOI 10.1101/2023.10.31.564967
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