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Article

Biomarker signatures of quality for nasal chondrocyte-derived engineered cartilage

2020-02-13

Abstract excerpt

The definition of quality controls for cell therapy and engineered product manufacturing processes is critical for safe, effective, and standardized clinical implementation. Using the example context of cartilage grafts engineered from autologous nasal chondrocytes, currently used for articular cartilage repair in a phase II clinical trial, we outlined how gene expression patterns and generalized linear models can...

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Identifiers and source

Literature Corpus work
e204aec8-ad22-59bc-9e74-5f658738c213
DOI
10.1101/2020.02.12.945527
Open publication

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