Article

Molecular Complexity of MDS and AML with Aberrations of Chromosome 7

2025-09-12

Abstract excerpt

Complete or partial deletions of chromosome 7 (-7/del7q) represent the most frequent chromosomal abnormalities observed in myeloid neoplasms (MNs) and are associated with a poor prognosis. -7/del7q are observed in 10-15% of adult patients with myelodysplasia (MDS) or with acute myeloid leukemia (AML). The occurrence of -7/del7q is particularly frequent in pediatric MDS, often associated with germline mutations of...

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Literature Corpus work: e2032203-a575-5bf3-82df-3728bd60f636
DOI: 10.20944/preprints202509.1101.v1

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