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Multi-trait Analysis of GWAS for circulating FGF23 Identifies Novel Network Interactions Between HRG-HMGB1 and Cardiac Disease in CKD

2024-03-06

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Genome-wide association studies (GWAS) have identified numerous genetic loci associated with mineral metabolism (MM) markers but have exclusively focused on single-trait analysis. In this study, we performed a multi-trait analysis of GWAS (MTAG) of MM, exploring overlapping genetic architecture between traits, to identify novel genetic associations for fibroblast growth factor...

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Literature Corpus work
e05dfccf-381e-54ba-a261-5ec531b20178
DOI
10.1101/2024.03.04.24303051
Open publication

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Multi-trait Analysis of GWAS for circulating FGF23 Identifies Novel Network Interactions Between HRG-HMGB1 and Cardiac Disease in CKDDOI 10.1101/2024.03.04.24303051
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