Article

Restoration of Keratinocyte Homeostasis Drives Resolution of Skin Inflammation

2026-03-04

Abstract excerpt

Chronic skin inflammation is sustained by reciprocal interactions between epidermal dysfunction and immune activation, yet whether epithelial state actively governs restoration of tissue homeostasis remains unclear. Using a murine model of inflammatory skin disease, we modulated epidermal lipid metabolism and examined its effects on tissue organization. Transcriptomic profiling revealed coordinated reversal of inf...

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Literature Corpus work: e05b84db-c710-576e-bb6b-45939455f3ae
DOI: 10.64898/2026.03.04.708224

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