Article

Fine-Tuning Protein Language Models Unlocks the Potential of Underrepresented Viral Proteomes

2025-04-23

Abstract excerpt

<h4>ABSTRACT</h4> Protein language models (pLMs) have revolutionized computational biology by generating rich protein vector representations—or embeddings—enabling major advancements in de novo protein design, structure prediction, variant effect analysis, and evolutionary studies. Despite these breakthroughs, current pLMs often exhibit biases against proteins from underrepresented species, with viral proteins be...

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Literature Corpus work: e04b3ada-faff-58b9-83b1-2e1fd2f9a8cc
DOI: 10.1101/2025.04.17.649224

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