Contact area and tissue growth dynamics shape synthetic juxtacrine signaling patterns

Abstract excerpt

Cell-cell communication through direct contact, or juxtacrine signaling, is important in development, disease, and many areas of physiology. Synthetic forms of juxtacrine signaling can be precisely controlled and operate orthogonally to native processes, making them a powerful reductionist tool with which to address fundamental questions in cell-cell communication in vivo . Here we investigate how cell-cell conta...

Topics

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• Body Patterning
• Cell Division
• Cell Movement
• Cell Proliferation
• Cellular Microenvironment
• Computer Simulation
• Models, Biological
• Mutation

Identifiers and source

Literature Corpus work

df8b3be3-70b1-5112-8c70-0112cd2a7487

DOI

10.1101/2023.07.12.548752