Drosophila genetic variants that change cell size and rate of proliferation affect cell communication and hence patterning.

doi:10.1016/j.mod.2004.02.007

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Article

Drosophila genetic variants that change cell size and rate of proliferation affect cell communication and hence patterning.

Mechanisms of development - 1 Apr 2004

Resino Jaime, García-Bellido Antonio

Abstract excerpt

We explore in this paper the role of genetic variants that affect cell size and proliferation in the determination of organ size. We use genetic mosaics of loss or gain of function in six different loci, which promotes smaller or larger than normal cells, associated to either smaller or larger than normal territories. These variants have autonomous effects on patterning and growth in mutant territories. However,...

Topics

Animals
Body Patterning
Cell Communication
Cell Cycle Proteins
Cell Division
Cell Size
Drosophila
Drosophila Proteins
Phenotype
Wings, Animal

Source

Open in PubMed

Identifiers

PMID: 15110045
DOI: 10.1016/j.mod.2004.02.007

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