Article

DEF6 regulates renal ischemia reperfusion injury through suppressing the WWP2 mediated ubiquitination of PARP1

2024-09-12

Abstract excerpt

<title>Abstract</title> <p>Background Renal ischemia-reperfusion injury (RIRI) stands as an unavoidable complication arising from kidney surgery, profoundly intertwined with its prognosis. The role of differentially expressed in FDCP 6 homolog (DEF6) in RIRI remains elusive, despite its confirmation as a potential therapeutic target for diverse diseases. Here, we investigated the mechanism by which DEF6 regulate...

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Literature Corpus work: 69cb55be-74ce-5f14-a01e-e0486adae22e
DOI: 10.21203/rs.3.rs-4867731/v1

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DEF6 regulates renal ischemia reperfusion injury through suppressing the WWP2 mediated ubiquitination of PARP1DOI 10.21203/rs.3.rs-4867731/v1Read

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