Article

The role of non-coding tandem repeat DNA and non-LTR retrotransposons in Amyotrophic Lateral Sclerosis risk loci

2021-01-01

Abstract excerpt

Genome-wide association studies and functional data have shown that there is a genetic basis contributing to sporadic and familial forms of amyotrophic lateral sclerosis (ALS), with a vast plethora of genes being associated with the disease. Since the discovery of the C9orf72 intronic repeat expansion there has been a growing awareness of non-coding repetitive DNA being associated with ALS risk. Originally labelle...

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Literature Corpus work: df3d7052-73bf-5d1a-9ad2-7b8f3f4d911d
DOI: 10.17638/03116866

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