Article

The conservation of human functional variants and their effects across mammals

2022-04-12

Abstract excerpt

Despite the clear potential of livestock models of human functional variants to provide important insights into the biological mechanisms driving human diseases and traits, their use to date has been limited. Generating such models via genome editing is costly and time consuming, and it is unclear which variants will have conserved effects across species. In this study we address these issues by studying naturally...

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Literature Corpus work: df2d6f23-8130-5c39-83cd-53abd1cfad3c
DOI: 10.1101/2022.04.11.487854

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