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Article

Complete Complement Factor I (CFI) deficiency: a systematic review of forty-nine patients including three novel cases.

BMC immunology - 26 Jul 2025

Rajabi Erta, Kheirabadi Mahsa Choroom, Olyaei Nasrin Alipour, Molitor Anne, Khorshidi Mohadese Sadat Mousavi, Heidari Morteza, Abbasi Arash, Rostami Parastoo, Mahdavi Mohadese, Carapito Raphael, Shahrooei Mohammad, Bahram Seiamak, Parvaneh Nima

Abstract excerpt

BACKGROUND: Complete complement factor I (CFI) deficiency is an inborn error of immunity (IEI) that results in heightened susceptibility to infections and immune dysregulatory disorders. This systematic review seeks to enhance our understanding of the clinical characteristics, genotype-phenotype correlations, and treatment outcomes in patients with complete CFI deficiency, including three novel cases. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40713518
DOI: 10.1186/s12865-025-00739-y
PMCID: PMC12297857

Genes

CFI
C3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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Complete Complement Factor I (CFI) deficiency: a systematic review of forty-nine patients including three novel cases.PMID 40713518Read ↗

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