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Identification and validation of SUN modification-related anti-PD-1 immunotherapy-resistance signatures to predict prognosis and immune microenvironment status in glioblastoma

2025-06-13

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Ubiquitination, SUMOylation, and neddylation (collectively termed SUN modifications) play crucial roles in cancer pathogenesis and immunotherapy resistance. This study investigated the prognostic significance of these modifications in glioblastoma (GBM). <bold>Methods:</bold> Key genes associated with SUN modifications and anti-PD-1 resistance were identifi...

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Literature Corpus work
df17b98e-63b8-583e-b841-611584fb56fc
DOI
10.21203/rs.3.rs-6838293/v1
Open publication

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Identification and validation of SUN modification-related anti-PD-1 immunotherapy-resistance signatures to predict prognosis and immune microenvironment status in glioblastomaDOI 10.21203/rs.3.rs-6838293/v1
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