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WITHDRAWN: Identification of SUMOylation biomarkers in glioblastoma based on transcriptome and Mendelian randomization combined with single-cell RNA-seq analysis

2025-03-11

Abstract excerpt

<title>Abstract</title> <p>Aberrant SUMOylation has been associated with cancer, neurodegenerative diseases, and infections, but its exact role in glioblastoma (GBM) remains unknown. This study aimed to uncover this link and identify novel biomarkers for GBM treatment. NPC2, SPI1, and LRRC25 were identified as prognostic biomarkers for GBM outcomes. MR analysis showed that NPC2 and LRRC25 increased GBM risk, whil...

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Literature Corpus work: 29a82ada-626f-52a0-8e10-3fcc21d9148c
DOI: 10.21203/rs.3.rs-6097394/v1

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