Article

The potential prognostic and immunological roles of N7-methylguanosine (m7G) in uveal melanoma

2023-11-21

Abstract excerpt

<h4>Objective: </h4> Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. Recently, RNA modifications have received increasing attention and have been shown to regulate tumorigenesis and immune response. However, the specific roles of N7-methylguanosine (m7G) on the prognosis, tumour immune microenvironment and immunotherapy in UM remain poorly understood. Methods Gene expression data...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: a77a37b5-55c6-5be3-911e-e400649702b0
DOI: 10.21203/rs.3.rs-3625755/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The potential prognostic and immunological roles of N7-methylguanosine (m7G) in uveal melanomaDOI 10.21203/rs.3.rs-3625755/v1Read

The prognostic values of m6A RNA methylation regulators in Uveal melanomaSemantic proximity Read

The prognostic values of m6A RNA methylation regulators in uveal melanomaSemantic proximity Read

Identification of prognostic genes in uveal melanoma microenvironmentSemantic proximity Read

An 11‐gene‐based prognostic signature for uveal melanoma metastasis based on gene expression and DNA methylation profileSemantic proximity Read

Genetic and epigenetic insights into uveal melanomaSemantic proximity Read

Hypomethylation of CD3D promoter induces immune cell infiltration and supports malignant phenotypes in uveal melanoma.Semantic proximity Read

Role of m6A modification in stromal and immune activation patterns together with response to ICI in melanomaSemantic proximity Read

[Application of next-generation sequencing in the pathogenesis of uveal melanoma].Semantic proximity Read

Construction of a Promising Tumor-Infiltrating CD8+ T Cells Gene Signature to Improve Prediction of the Prognosis and Immune Response of Uveal MelanomaSemantic proximity Read

Role of Epigenetics in Uveal MelanomaSemantic proximity Read

Machine learning-based integrative analysis of methylome and transcriptome identifies novel prognostic DNA methylation signature in uveal melanomaSemantic proximity Read

Identification of prognostic m 6 A modification patterns and score system in melanoma patientsSemantic proximity Read