Article

Novel insights into the structure and transport mechanisms of TAPT1

2020-05-20

Abstract excerpt

Transmembrane anterior-posterior transformation protein 1 (TAPT1), encoded by the TAPT1 gene expressed in the basal ciliary body, plays a crucial role in cilia formation as well as axial skeletal patterning. Mutations in this gene have been reported to cause several ciliopathies and osteo-related diseases. Unfortunately, the cellular and molecular pathogenic mechanisms are still unclear also due to the lack of X-...

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Literature Corpus work: df0c7b09-f26e-51ae-8275-3b4da31b73d2
DOI: 10.1101/2020.05.18.099887

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