Article

Integrative transcriptomic profiling reveals convergent coding and non-coding signatures in pediatric bone marrow failure syndromes

2026-04-07

Abstract excerpt

<title>Abstract</title> <p> Pediatric bone marrow failure (BMF) comprises heterogeneous inherited and immune-mediated disorders, yet many cases remain genetically unclassified despite comprehensive genomic evaluation. To identify shared transcriptional features beyond protein-coding variation, we performed total RNA sequencing on bone marrow samples from pediatric BMF patients (n=12) and controls (n=2). Based on...

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Literature Corpus work: df023628-ca98-5e5a-80ec-62d0598d8703
DOI: 10.21203/rs.3.rs-9165159/v1

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