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MiGut: a scalable <i>in vitro</i> platform for simulating the human gut microbiome – development, validation, and simulation of antibiotic induced dysbiosis

2022-09-02

Abstract excerpt

In vitro models of the human colon have been used extensively in developing understanding of the human gut microbiome and how internal and external factors affect the residing bacterial populations. Such models can be highly predictive of in vivo effects of antibiotics, and indeed more so than animal models. The complexity required by current in vitro models to closely mimic the physiology of the colon poses pra...

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Literature Corpus work
ded6d9d5-7c94-53d5-aea9-785918a15459
DOI
10.1101/2022.09.02.506309
Open publication

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