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Sedative Potential of Catha edulis Forsk: Exploring In Vivo Model, Gene Expression, Molecular Docking, and GABAergic Pathway Involvement

2024-05-16

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<title>Abstract</title> <p>Background Laboratory studies and traditional reports have linked Catha edulis (khat) to biopharmacological properties. This study aimed to assess the sedative effect of khat in mice and conduct computer-aided docking of GABA<sub>A</sub> receptors. Methods Liquid chromatography-mass spectrometry (LC-MS) analysis confirmed the presence of cathinone and cathine, the active alkaloids, in...

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Literature Corpus work
dec39455-eb34-5a63-bb52-2b3fa72a3d8d
DOI
10.21203/rs.3.rs-4364720/v1
Open publication

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Sedative Potential of Catha edulis Forsk: Exploring In Vivo Model, Gene Expression, Molecular Docking, and GABAergic Pathway InvolvementDOI 10.21203/rs.3.rs-4364720/v1
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