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Article

Clinical Implications of <i>MET</i> Gene Copy Number in Lung Cancer

10 Feb 2010

Abstract excerpt

MET, the receptor for HGF, has recently been identified as a novel promising target in several human malignancies, including non-small-cell lung cancer (NSCLC). Deregulation of the HGF/MET signaling pathway can occur via different mechanisms, including HGF and/or MET overexpression, MET gene amplification, mutations or rearrangements. While the role of MET mutations in NSCLC is not yet fully understood, MET...

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PMID: 20146583
DOI: 10.2217/fon.09.164

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