Article

Clinical Features and Prospective Outcomes of Thin Filament Hypertrophic Cardiomyopathy: Intrinsic Data and Comparative Insights from Other Cohorts

2025-01-03

Abstract excerpt

<h4>Background: </h4> /Objectives: Hypertrophic cardiomyopathy (HCM) is the most common genetic heart disease. The most frequently mutated genes encode proteins of the thick filament of the sarcomere, while mutations in thin filament genes are rare findings in HCM cohorts. Recent studies have revealed distinct mechanisms of disease development linked to thin filament mutations, highlighting the need for further in...

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Literature Corpus work: dea845ed-af49-5175-a325-7735e870e051
DOI: 10.20944/preprints202412.2655.v1

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