Article

Outcomes and phenotypic expression of rare variants in hypertrophic cardiomyopathy genes amongst UK Biobank participants

2021-01-26

Abstract excerpt

<h4>Background</h4> Hypertrophic cardiomyopathy (HCM) is caused by rare variants in sarcomere-encoding genes, but little is known about the clinical significance of these variants in the general population. <h4>Methods</h4> We compared outcomes and cardiovascular phenotypes in UK Biobank participants with whole exome sequencing stratified by sarcomere-encoding variant status. <h4>Results</h4> The prevalence of rar...

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Literature Corpus work: 0e3e5a95-4d91-5459-8e38-1c21b8cac068
DOI: 10.1101/2021.01.21.21249470

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