Article

Lethal and nonlethal chromosome aberrations by gamma rays and heavy ions: a cytogenetic perspective on dose fractionation in hadron radiotherapy

2017-07-01

Abstract excerpt

Background: With ions heavier than protons now being used in radiotherapy, consideration has been given to the use of fewer dose fractions. Because it is among the best surrogate measures of cell killing and carcinogenic potential, damage to chromosomes relates to the clinical objectives of minimizing normal tissue damage, and lessening the chance of treatment-related second cancers. Curvature in acute dose respon...

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Literature Corpus work: de92c7c5-1f79-521c-b1ab-cc84420329e3
DOI: 10.21037/tcr.2017.05.16

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