Article

Non-driver mutations landscape in different stages of primary myelofibrosis determined ASXL1 mutations play a critical role in disease progression

2023-02-10

Abstract excerpt

<title>Abstract</title> <p>Except for driver mutations (<italic>JAK2</italic>, <italic>MPL</italic>, <italic>CALR</italic>), primary myelofibrosis (PMF) patients have much more non-driver mutations than polycythemia vera (PV) and essential thrombocythemia (ET) patients. The relationship between disease progression (prefibrotic (Pre) to overtfibrotic (Overt) to accelerate phase/blast phase (AP/BP)) and non-driver...

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Literature Corpus work: de7583aa-715c-566f-b241-98f9156e776e
DOI: 10.21203/rs.3.rs-2536643/v1

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