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Article

A case of a primary myelofibrosis with progression and related literature review of progression phase genetics.

International journal of laboratory hematology - 1 Jul 2021

Chen Dong, Fuda Franklin, Weinberg Olga

Abstract excerpt

Philadelphia (BCR-ABL)-negative myeloproliferative neoplasms (MPNs) include polycythemia vera (PV), essential thrombocythemia (ET), and primary myelofibrosis (PMF). MPN can transform into an accelerated or a blast phase, which is associated with poor response to standard therapy and low overall median survival. We present an interesting case of a patient with a history of PMF and progression and summarize the...

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Identifiers

PMID: 34288445
DOI: 10.1111/ijlh.13565

Genes

ASXL1
BCR
IDH1
SRSF2
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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