Back to search

Article

Brain Insulin Resistance: Focus on Insulin Receptor-Mitochondria Interactions

2021-03-15

Abstract excerpt

Current hypotheses implicate insulin resistance of the brain as a pathogenic factor in the development of Alzheimer’s disease and other dementias, Parkinson’s disease, type 2 diabetes, obesity, major depression, and traumatic brain injury. A variety of genetic, developmental, and metabolic abnormalities that lead to disturbances in the insulin receptor signal transduction may underlie insulin resistanc...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
de516479-3889-5291-b611-8d94fe85693b
DOI
10.20944/preprints202103.0401.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Brain Insulin Resistance: Focus on Insulin Receptor-Mitochondria InteractionsDOI 10.20944/preprints202103.0401.v1
Brain Insulin Resistance: Focus on Insulin Receptor-Mitochondria InteractionsSemantic proximity
Unraveling The Mystery of Insulin Resistance: From Principle Mechanistic Insights and Consequences to Therapeutic InterventionsSemantic proximity
Insulin and Its Key Role for Mitochondrial Function/Dysfunction and Quality Control: A Shared Link between Dysmetabolism and NeurodegenerationSemantic proximity
Insulin Resistance and Diabetes Mellitus in Alzheimer’s DiseaseSemantic proximity
The Role of Mitochondria in the Pathophysiology of Skeletal Muscle Insulin ResistanceSemantic proximity
Insulin and Autophagy in NeurodegenerationSemantic proximity
Alzheimer's Disease and Diabetes: An Integrative View of the Role of Mitochondria, Oxidative Stress, and InsulinSemantic proximity
Chronically Increased Levels of Circulating Insulin Secondary to Insulin Resistance: A Silent KillerSemantic proximity
Insulin Resistance Syndrome- the Sensitive IRSSemantic proximity
Insulin receptor signaling in normal and insulin-resistant states.Semantic proximity
Mitochondrial dysfunction and insulin resistance: an updateSemantic proximity
Molecular biology of insulin resistance.Semantic proximity
Select a neighboring publication to make it the new centre.