Article
Brain Insulin Resistance: Focus on Insulin Receptor-Mitochondria Interactions
2021-03-15
Abstract excerpt
Current hypotheses implicate insulin resistance of the brain as a pathogenic factor in the development of Alzheimer’s disease and other dementias, Parkinson’s disease, type 2 diabetes, obesity, major depression, and traumatic brain injury. A variety of genetic, developmental, and metabolic abnormalities that lead to disturbances in the insulin receptor signal transduction may underlie insulin resistanc...
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Identifiers and source
- Literature Corpus work
- 954b7fdd-ef5e-501b-90a5-6691276ccfd3
- DOI
- 10.20944/preprints202103.0372.v1
